Is Evidence for Homeopathy Reproducible? A Closer Look at the Reilly Study
By John Melnychuck, RSHom (NA)

Homeopathy has long been a subject of intense debate within the scientific and medical communities. Critics often dismiss it as pseudoscience, attributing its effects to the placebo response. Yet, a groundbreaking clinical trial conducted by David Taylor Reilly and his team, published in The Lancet in December 1994, challenges this narrative. The study, conducted at the Glasgow Royal Infirmary, provides compelling evidence that homeopathically potentized substances have a measurable effect beyond placebo, raising important questions about the nature of homeopathy and its place in modern medicine.
The Study: A Scrupulous Examination of Homeopathic Potencies
Reilly’s study was designed to test the effects of “homeopathically potentized” allergens (diluted to 30CH) on asthma patients who exhibited sensitivity to specific allergens, such as dust mites, animal fur, pollens, and the Cladosporium fungus. The trial was conducted as a double-blind, placebo-controlled study, adhering to the rigorous standards of the Western scientific method.
The results were striking: patients who received the potentized allergens experienced greater symptom relief compared to those who received a placebo. This outcome was consistent with two earlier trials conducted by the same team, further reinforcing the reproducibility of the findings. Importantly, the study demonstrated that the effects of homeopathic preparations were not merely placebo-driven but had a measurable biological impact.
Isopathy vs. Classical Homeopathy: A Nuanced Distinction
While the study’s results are encouraging for proponents of homeopathy, it’s important to note that the trial focused on isopathy—a subset of homeopathy that uses potentized forms of the causative agent (in this case, allergens) rather than individualized remedies based on the totality of symptoms, as classical homeopathy prescribes.
This distinction has led some homeopaths to critique the study’s parameters, arguing that the narrow focus on pathological symptoms and the use of a complex formula (rather than single remedies) deviate from traditional homeopathic practice. Nevertheless, the study’s success in demonstrating the biological activity of potentized substances is a significant step forward, even if it doesn’t fully align with the holistic principles of homeopathy.
A Dilemma for Homeopathy: Reductionism vs. Synthesism
The study also highlights a fundamental tension between homeopathy and conventional science. Homeopathy operates on a principle of synthesism, considering the whole person and their unique symptom picture, while conventional science relies on reductionism, breaking down phenomena into isolated variables for study.
Reilly and his team navigated this tension by designing a study that met the rigorous standards of conventional science, even if it didn’t fully capture the holistic essence of homeopathy. In doing so, they achieved a remarkable feat: producing reproducible evidence that potentized substances have a measurable effect, challenging the prevailing assumption that homeopathy relies solely on placebo.
A Landmark Achievement in Homeopathic Research
The study’s success lies not only in its results but also in its methodology and collaborative spirit. Reilly and his team brought together a diverse group of participants and supporters from both the homeopathic and allopathic communities, demonstrating a rare level of cooperation and professionalism. The study’s meticulous planning, execution, and evaluation set a new standard for research in this field.
Moreover, the study’s findings carry significant implications for the future of homeopathy. By providing reproducible evidence of the biological activity of potentized substances, it opens the door for further research and dialogue between homeopaths and the scientific community. As Reilly et al. aptly concluded, “homeopathy differs from placebo in an inexplicable, but reproducible way.”
A Step Forward for Homeopathy
While the Reilly study may not satisfy all homeopaths or skeptics, it represents a crucial milestone in the ongoing effort to validate homeopathy within the framework of conventional science. It challenges the dismissive narrative that homeopathy is mere quackery and provides a foundation for future studies to build upon.
For those of us who practice and believe in homeopathy, this study is a reminder of the importance of engaging with the scientific community, even if it means navigating the complexities of reductionist research. It also underscores the need for continued collaboration and innovation in our quest to understand and harness the power of potentized substances.
In the end, the Reilly study is not just about proving homeopathy’s efficacy—it’s about fostering a spirit of curiosity, openness, and cooperation that can bridge the gap between homeopathy and conventional medicine. And that, in itself, is a victory worth celebrating.
John Melnychuck, RSHom (NA), lives and practices in Menlo Park, California.